Name | Lauroyl chloride |
Synonyms | LACL Lauric chloride Lauroyl chloride LAUROYL CHLORIDE DODECANOYL CHLORIDE Dodecanoyl chloride LAURIC ACID CHLORIDE n-Dodecanoyl Chloride N-DODECANOYL CHLORIDE dodecanoicacid,chloride |
CAS | 112-16-3 |
EINECS | 203-941-7 |
InChI | InChI=1/C12H23ClO/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3 |
InChIKey | NQGIJDNPUZEBRU-UHFFFAOYSA-N |
Molecular Formula | C12H23ClO |
Molar Mass | 218.76 |
Density | 0.946 g/mL at 25 °C (lit.) |
Melting Point | -17 °C |
Boling Point | 134-137 °C/11 mmHg (lit.) |
Flash Point | >230°F |
Water Solubility | reacts |
Solubility | Soluble in ethanol and methanol. |
Vapor Presure | 0.5Pa at 20℃ |
Appearance | Liquid |
Color | Clear |
BRN | 1281201 |
Storage Condition | Store below +30°C. |
Stability | Stable. Incompatible with strong oxidizing agents, amines, strong bases. Do not allow to come into contact with water or moisture. |
Sensitive | Moisture Sensitive |
Refractive Index | n20/D 1.445 |
Physical and Chemical Properties | Density 0.946 melting point -17°C boiling point 134-137 ° C (11 mmHg) refractive index 1.444-1.446 flash point 140°C water-soluble acts |
Use | Used as a surfactant and other organic chemical synthesis acylating agent |
Hazard Symbols | C - Corrosive |
Risk Codes | R34 - Causes burns R37 - Irritating to the respiratory system R29 - Contact with water liberates toxic gas R22 - Harmful if swallowed R14 - Reacts violently with water |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S8 - Keep container dry. |
UN IDs | UN 3265 8/PG 2 |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29159080 |
Hazard Class | 8 |
Packing Group | II |
Toxicity | LD50 orally in Rabbit: 200 - 2000 mg/kg |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | is useful as an intermediate in pharmaceutical and organic synthesis. used as a surfactant and other organic chemical synthesis of acylating agent |
production method | is obtained by reacting lauric acid with thionyl chloride. Thionyl chloride was added dropwise to lauric acid, heated to 75 °c, stirred for 2H, then warmed to 90 °c and refluxed for 2H. The reaction mixture was then fractionated by distilling off excess thionyl chloride under reduced pressure and collecting the 146-150 ° C. (2.13-2.27kPa) fraction as dodecanoyl chloride. The yield was about 80%. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |